Research & Development

Research: The bridge to outstanding therapies

Mission Pharmacal Company has distinguished itself with its continued commitment to in-house research and development. Mission has a team of highly qualified (Ph.D., M.S. and B.S.) and experienced pharmaceutical scientists. Research continues in the advancement of new chemical entities and products which show great promise in the treatment of a variety of disease states. Mission also has experienced clinical researchers who write research and clinical protocols for preclinical and clinical studies. Mission has a pipeline of technology that will serve the medical community, patients, and consumers for years to come.

Transforming orphan drugs into major advancements

Historically, Mission Pharmacal has directed much of its resources to the research and development of therapeutics and diagnostic procedures for the treatment and prevention of kidney stone disease. A strong commitment to this "Orphan Disease" has led to the development and marketing of: Urocit®-K (5 mEq, 10 mEq and 15 mEq strengths), Lithostat® and Thiola®. These innovative drugs are considered major advances in the medical management of kidney stone disease. In recognition of our efforts, the National Organization for Rare Disorders has acknowledged Mission Pharmacal by awarding it the Corporate Leadership Award in observance of the 10th anniversary of the Orphan Drug Act.

Today, research continues in the advancement of new therapies. Mission intends to move forward, within the framework of sound research, development and clinical expertise, to expand its capabilities, thus providing outstanding therapeutics well into the future.

R&D Scope

  • Product development (ingredient sourcing, formulation development and analytical method development) of solid oral dosage forms and semisolid topicals.
  • Process development from pilot stage through production scale.
  • Small-scale and pilot capability for powder blending, milling, particle sizing, wet/dry granulation, tablet compression (immediate release and controlled release) and tablet coating (aqueous and solvent based coatings).

Analytical Methods Development and Validation

  • High Performance Liquid Chromatography
  • Gas Chromatography
  • Ion Chromatography
  • Atomic Absorption Spectrophotometry
  • Near IR
  • Fluorescence Scanning Spectrophotometry
  • USP Type 1 and 2 Dissolution